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EMAGE:737

Shh sonic hedgehog ( MGI:98297)
TS17 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:737 EMAGE:737
Figure 4D of Kruger et al., 2001 [PMID:11171399] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright. Figure 4A of Kruger et al., 2001 [PMID:11171399] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
The section shown in figure D is taken from the wholemount shown in figure A.
Expression Pattern Description
Spatial Annotation:
EMAGE:737EMAGE:737Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
737_voxel_strong_3D_1.wlz
737_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:737_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
limb
detected detected
regionalPresent in the posterior margin (of the limb), in the zone of polarizing activity.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2148851
Entity Detected:Shh, sonic hedgehog ( MGI:98297)
Notes:The Shh probe used in this study by Kruger et al., 2001 [PMID:11171399] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS17
Mutations:none (wild-type)
Preparation:wholemount plus section of wholemount
Procedures
Embedding:gelatin
General Information
Authors:Kruger et al., 2001 [PMID:11171399] Indexed by GXD, Spatially mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:11171399] Kruger M, Mennerich D, Fees S, Schafer R, Mundlos S, Braun T 2001 Sonic hedgehog is a survival factor for hypaxial muscles during mouse development. Development (128):743-52
Links:MGI:2149577 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI