Quicksearch Help

(Click the icon to keep this page displayed.)

EMAGE:840

Pitx2 paired-like homeodomain transcription factor 2 ( MGI:109340)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:840 EMAGE:840
Figure 1F' of Kitamura et al., 1999 [PMID:10572050] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright. Figures 1A,B of Kitamura et al., 1999 [PMID:10572050] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Image annotation: hm - head mesoderm. The probe utilised in this study detects both the Pitx2a and Pitx2b splice forms of Pitx2.
Expression Pattern Description
Spatial Annotation:
EMAGE:840EMAGE:840Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
840_voxel_moderate_3D_1.wlz
840_voxel_weak_3D_1.wlz
840_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:840_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
head mesenchyme
moderate moderate
homogeneous
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1347570
Entity Detected:Pitx2, paired-like homeodomain transcription factor 2 ( MGI:109340)
Notes:The Pitx2 probe used is this study by Kitamura et al., 1999 [PMID:10572050] was "prepared from cDNA equivalent to exon I/exonII." The exact sequence of unspecified however this probe detects both the Pitx2a and Pitx2b splice forms of Pitx2 (see Figs 1A,B).
Chemistry:RNA
Strand:antisense
Label:S35
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:section
Procedures
Staining procedure:autoradiography
General Information
Authors:Kitamura et al., 1999 [PMID:10572050] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10572050] Kitamura K, Miura H, Miyagawa-Tomita S, Yanazawa M, Katoh-Fukui Y, Suzuki R, Ohuchi H, Suehiro A, Motegi Y, Nakahara Y, Kondo S, Yokoyama M 1999 Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism. Development (126):5749-58
Links:MGI:1347774 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI