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EMAGE:960

Shh sonic hedgehog ( MGI:98297)
TS15 (9.5 dpc)
in situ hybridisation

Data Images
EMAGE:960
Figure 3D of Bai et al., 2002 [PMID:12361967] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: three stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Expression Pattern Description
Spatial Annotation:
EMAGE:960Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
960_wholemount_strong_3D_1.wlz
960_wholemount_moderate_3D_1.wlz
960_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:960_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
notochord
detected detected
Expression in floor plate throughout the anterior/posterior axis.
rhombomere 06 floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
telencephalon floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
rhombomere 08 floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
rhombomere 01 floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
rhombomere 02 floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
rhombomere 03 floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
rhombomere 04 floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
rhombomere 05 floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
diencephalon floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
rhombomere 07 floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
future midbrain floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
neural tube floor plate
detected detected
Expression in floor plate throughout the anterior/posterior axis.
future forebrain
detected detected
regionalExpression along the sulcus limitans in the forebrain.
gut
detected detected
regionalExpression in the gut endoderm.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3047265
Entity Detected:Shh, sonic hedgehog ( MGI:98297)
Notes:The Shh probe used in this study by Bai et al., 2002 [PMID:12361967] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:9.5 dpc
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Bai et al., 2002 [PMID:12361967] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:12361967] Bai CB, Auerbach W, Lee JS, Stephen D, Joyner AL 2002 Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development (129):4753-61
Links:MGI:2676443 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI