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EMAGE:989

Bmp4 bone morphogenetic protein 4 ( MGI:88180)
TS15 (25 Somite no.)
in situ hybridisation

Data Images
EMAGE:989
Figure 4F of Houzelstein et al., 1999 [PMID:10331980] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: one star
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: 9, 14 refer to somites 9 and 14. Arrows delineate Bmp4 expression in the forelimb mesenchyme facing somites 11-15.
Expression Pattern Description
Spatial Annotation:
EMAGE:989Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
989_wholemount_strong_3D_1.wlz
989_wholemount_moderate_3D_1.wlz
989_wholemount_weak_3D_1.wlz
989_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:989_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: three stars
Text Annotation:
StructureLevelPatternNotes
forelimb bud mesenchyme
weak weak
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:1336795
Entity Detected:Bmp4, bone morphogenetic protein 4 ( MGI:88180)
Notes:The probe used in this study by Houzelstein et al., 1999 [PMID:10331980] "contains the 3' UTR and most of the coding sequence from a mouse cDNA (Jones et al., 1991 [PMID:1893873] ...(a kind gift from B. Hogan)". However, there is no probe described in Jones et al. that "contains the 3' UTR and most of the coding sequence".
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:25 Somite no.
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Houzelstein et al., 1999 [PMID:10331980] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:10331980] Houzelstein D, Auda-Boucher G, Cheraud Y, Rouaud T, Blanc I, Tajbakhsh S, Buckingham ME, Fontaine-Perus J, Robert B 1999 The homeobox gene Msx1 is expressed in a subset of somites, and in muscle progenitor cells migrating into the forelimb. Development (126):2689-701
 [ PMID:1893873] Jones CM, Lyons KM, Hogan BL 1991 Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. Development (111):531-42
Links:MGI:1336914 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI