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EMAGE:990

Bmp4 bone morphogenetic protein 4 ( MGI:88180)
TS20 (12.5 dpc)
in situ hybridisation

Data Images
EMAGE:990
Figure 5C of Ligon et al., 2003 [PMID:12668639] . Copyright: This image is from Development and is displayed with permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar expression patterns: Find spatially similar patterns
Notes:
Abbreviation used: cpp, choroid plexus primordium. Bracket delineates the cortical hem.
Expression Pattern Description
Spatial Annotation:
EMAGE:990EMAGE:990Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
3D mapping3D context movie

View mapped 3D expression image EMAGE genex expression entry
Download individual expression domains:
990_voxel_strong_3D_1.wlz
990_voxel_moderate_3D_1.wlz
990_voxel_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:990_all_domains.zip
Find spatially similar expression patterns: EMAGE spatially similar patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
telencephalon
detected detected
regionalExpression was detected in the roofplate organizer region.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2673451
Entity Detected:Bmp4, bone morphogenetic protein 4 ( MGI:88180)
Notes:The probe used in this study by Ligon et al., 2003 [PMID:12668639] was originally described in Lee et al., 2000 [PMID:10631167] . However, the details of the Bmp4 probe used by Lee et al are not described.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:12.5 dpc
Theiler Stage:TS20
Mutations:none (wild-type)
Preparation:section
Procedures
Fixation:4% paraformaldehyde
General Information
Authors:Ligon et al., 2003 [PMID:12668639] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.00421] [ PMID:12668639] Ligon KL, Echelard Y, Assimacopoulos S, Danielian PS, Kaing S, Grove EA, McMahon AP, Rowitch DH 2003 Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia. Development (130):2275-87
 [ PMID:10631167] Lee SM, Tole S, Grove E, McMahon AP 2000 A local Wnt-3a signal is required for development of the mammalian hippocampus. Development (127):457-67
Links:MGI:2673721 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI