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EMAGE:4625

Twsg1 twisted gastrulation homolog 1 (Drosophila) ( MGI:2137520)
TS16 (10.5 dpc)
in situ hybridisation

Data Images
EMAGE:4625
Figure 1D'. Copyright: This image is from Zakin L, Development 2005 May;132(10):2489-99 and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Expression pattern clarity: one star
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Note: Abbreviations: vm, ventral mesoderm; lb, limb bud; bt, basal telencephalon; md, mandibular component of first pharyngeal arch; mx, maxillary component of first pharyngeal arch.
Expression Pattern Description
Spatial Annotation:
EMAGE:4625Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
4625_wholemount_moderate_3D_1.wlz
4625_wholemount_possible_3D_1.wlz
4625_wholemount_notDetected_3D_1.wlz
4625_wholemount_strong_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:4625_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: two stars
Text Annotation:
StructureLevelPatternNotes
mesenchyme
detected detected
regionalExpression was detected in posterior ventral mesoderm.
limb
detected detected
1st branchial arch
detected detected
telencephalon
detected detected
regionalExpression was detected in basal telencephalon.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:3582774
Entity Detected:Twsg1, twisted gastrulation homolog 1 (Drosophila) ( MGI:2137520)
Notes:The Twsg1 probe used in this study by Zakin et al., 2005 [PMID:15843411] is indicated as that originally described in Zakin & De Robertis, 2004 [PMID:14681194] i.e. a full-length cDNA.
Chemistry:RNA
Strand:antisense
Specimen
Organism:mouse
Age:10.5 dpc
Theiler Stage:TS16
Mutations:none (wild-type)
Preparation:wholemount
Procedures
General Information
Authors:Zakin L; Reversade B; Kuroda H; Lyons KM; De Robertis EM, 2005 [PMID:15843411] . Indexed by GXD, Spatially mapped by EMAGE.
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ doi:10.1242/dev.01822] [ PMID:15843411] Zakin L, Reversade B, Kuroda H, Lyons KM, De Robertis EM 2005 Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development (132):2489-99
 [ doi:10.1242/dev.00946] [ PMID:14681194] Zakin L, De Robertis EM 2004 Inactivation of mouse Twisted gastrulation reveals its role in promoting Bmp4 activity during forebrain development. Development (131):413-24
Links:MGI:3582817 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI