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EMAGE:992

Pax6 paired box gene 6 ( MGI:97490)
TS15 (21 Somite no.)
in situ hybridisation

Data Images
EMAGE:992
Fig 2E of Ishibashi & McMahon, 2002 [PMID:12361972] Copyright: This image is from Development and is displayed with the permission of The Company of Biologists Ltd. who owns the copyright.

Expression pattern clarity: two stars
Find spatially similar wholemount expression patterns: Find spatially similar wholemount patterns
Notes:
Image annotations: arrowhead indicates the boundary between diencephalon and midbrain.
Expression Pattern Description
Spatial Annotation:
EMAGE:992Annotation colour key:  
strong strong      
gene expression moderate moderate    
gene expression weak weak        
gene expression possible possible    
gene expression not detected not detected
wholemount mapping

Download individual expression domains:
992_wholemount_strong_3D_1.wlz
992_wholemount_moderate_3D_1.wlz
992_wholemount_notDetected_3D_1.wlz
(what is wlz format?)
Download all expression domains: EMAGE:992_all_domains.zip
Find spatially similar wholemount expression patterns:  EMAGE spatially similar wholemount patterns
Morphological match to the template: one star
Text Annotation:
StructureLevelPatternNotes
diencephalon roof plate
detected detected
Expression in the forebrain terminates at the forebrain-midbrain boundary.
future midbrain
not detected not detected
telencephalon roof plate
detected detected
Expression in the forebrain terminates at the forebrain-midbrain boundary.
Annotation Validation: EMAGE Editor
Detection Reagent
Type:in situ hybridisation probe
Identifier:MGI:2676483
Entity Detected:Pax6, paired box gene 6 ( MGI:97490)
Notes:The Pax6 probe used in this study by Ishibashi & McMahon, 2002 [PMID:12361972] is of undefined sequence.
Chemistry:RNA
Strand:antisense
Label:digoxigenin
Specimen
Organism:mouse
Strain:Swiss
Age:21 Somite no.
Theiler Stage:TS15
Mutations:none (wild-type)
Preparation:wholemount
Procedures
Fixation:4% paraformaldehyde
Staining procedure:alkaline phosphatase + unspecified
General Information
Authors:Ishibashi & McMahon, 2002 [PMID:12361972] Indexed by GXD, Spatially Mapped by EMAGE
Submitted by:EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:non-screen
References:[ PMID:12361972] Ishibashi M, McMahon AP 2002 A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo. Development (129):4807-19
Links:MGI:2676607 same experiment
  Ensembl same gene
  Allen Brain Atlas same gene
  BioGPS same gene
  International Mouse Knockout Project Status same gene
  GEISHA Chicken ISH Database same gene
  EMBL-EBI Gene Expression Atlas same gene
  BrainStars same gene
  ViBrism same gene
Data SourceMGI