EMAGE mouse gene expression spatial database

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EMAGE:12071

Cxxc4 CXXC finger 4 ( MGI:2442112)
TS23 (14.5 dpc)
in situ hybridisation

Data Images


"Pseudo-wholemount" of euxassay_008607. This image has been made by aligning and collapsing the constitutent sections. Information about the method.	euxassay_008607_01	euxassay_008607_02	euxassay_008607_03	euxassay_008607_04

euxassay_008607_05	euxassay_008607_06	euxassay_008607_07	euxassay_008607_08	euxassay_008607_09

euxassay_008607_10	euxassay_008607_11	euxassay_008607_12	euxassay_008607_13	euxassay_008607_14

euxassay_008607_15	euxassay_008607_16	euxassay_008607_17	euxassay_008607_18	euxassay_008607_19

euxassay_008607_20	euxassay_008607_21	euxassay_008607_22	euxassay_008607_23	euxassay_008607_24

View assay images:
Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

12071_wholemount_strong.wlz

12071_wholemount_moderate.wlz

12071_wholemount_weak.wlz

12071_wholemount_possible.wlz

12071_wholemount_not_detected.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:12071_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

diaphragm

moderate

regional

moderate expression: see section 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24

forearm mesenchyme

strong

regional

strong expression: see section 01 02 03 04 05 06

upper arm mesenchyme

strong

regional

strong expression: see section 01 02 03 04 05 06 07

hand

strong

regional

strong expression: see section 03 04 05 06 07

foot

strong

regional

strong expression: see section 03 04 05 06 07 20

lower leg mesenchyme

strong

regional

strong expression: see section 01 02 03 04 05 06 08

upper leg mesenchyme

strong

regional

strong expression: see section 01 02 03 04 05 06 07 08 09 10

head mesenchyme

strong

regional

strong expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24

trunk mesenchyme

moderate

regional

moderate expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24

thymus primordium

weak

regional

weak expression: see section 13 14 15 16 17

pancreas

strong

regional

strong expression: see section 10 11 12 13 14 15 17 18 19 20

thyroid gland

strong

regional

strong expression: see section 17

brain

strong

regional

strong expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24

vibrissa

strong

regional

strong expression: see section 05 06 07 08 09 10 11 20 21 22 23 24

facial vii ganglion

strong

regional

strong expression: see section 05 06 07 08 20 21 22

glossopharyngeal ix ganglion

strong

regional

strong expression: see section 08 19 20 21

trigeminal v ganglion

strong

regional

strong expression: see section 04 05 06 07 08 09 10 18 19 20 21 22 23

vagus x ganglion

strong

regional

strong expression: see section 09 19

vestibulocochlear viii ganglion

strong

regional

strong expression: see section 07 08 09 18 19 20 21

trigeminal v nerve

strong

regional

strong expression: see section 10 18

spinal cord

strong

regional

strong expression: see section 11 12 13 14 15 16 17 18 19 20 21

cervico-thoracic ganglion

strong

regional

strong expression: see section 11 12 13 14 18

cervical ganglion

strong

regional

strong expression: see section 10 18 19

thoracic ganglion

strong

regional

strong expression: see section 14 15 16 17

dorsal root ganglion

strong

regional

strong expression: see section 09 10 11 12 13 14 15 18 19 20 21

neural retina

strong

regional

strong expression: see section 01 02 03 04 24

naris

strong

regional

strong expression: see section 13 14 15

anterior naris epithelium

strong

regional

strong expression: see section 17

nasal cavity olfactory epithelium

strong

regional

strong expression: see section 08 09 10 11 12 13 16 17 18 19 20

esophagus

moderate

regional

moderate expression: see section 15 16

tongue muscle

strong

regional

strong expression: see section 11 12 13 14 15 16 17 18 19

stomach

moderate

regional

moderate expression: see section 03 04 05 06 07 08 09 10 11 12

midgut

moderate

regional

moderate expression: see section 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22

lower jaw incisor

strong

regional

strong expression: see section 11 12 13 17 18 moderate expression: see section 16

lower jaw molar

strong

regional

strong expression: see section 07 08 20 21

upper jaw incisor

strong

regional

strong expression: see section 12 13 18 moderate expression: see section 16

upper jaw molar

strong

regional

strong expression: see section 08 20 21

bladder

strong

regional

strong expression: see section 17 moderate expression: see section 15 16

renal medullary interstitium

moderate

regional

moderate expression: see section 09 10 11 12 13 20 21 22 23 24

larynx

strong

regional

strong expression: see section 13 14 15

trachea

moderate

regional

moderate expression: see section 15 16

pelvic girdle skeleton

strong

regional

strong expression: see section 11 12 13

tail mesenchyme

strong

regional

strong expression: see section 10 11 12 13 14 15 16 17 18 19

Annotation Validation:

spatial mapping by EMAGE editor, text annotation by author

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	T9408
Entity Detected:	Cxxc4, CXXC finger 4 ( MGI:2442112)
Sequence:	sense strand is shown >T9408 TTCCCCCCCTGCACCATGAACACCAATGTCTGCGTGGAGCCCGGGCCGAGCCCGGAGGCCCCGGGCTTGC CCAAGGAAAGCCACCTGCCCGAGGGGGCCCTGAACAGCCTTGTGGATTACAACTCGGAGATGGAGCGTTA CCGCTCCTTTGCCACCTCCTTCTACAAGACCAACGGGGGCGCCTTCCCGCAGGCAGCCAAGATCGCGCGC ATCACCACCCCCATCTTCCCCGGCGGCAGGACCAGCATGCACCACCGGAACGACTCCCAGCGGCTGGGGA AGGCTGGCTGTCCGCCAGAGCCGTCGTTGCAAATGGCAAATACTAATTTCCTCTCCACCTTATCCCCCGA ACACTGCAGACCTTTGGCGGGGGAATGCATGAACAAGCTCAAATGCGGCGCTGCTGAAGCAGAGATAATG AATCTCCCCGAGCGGGTGGGGACTTTTTCCGCTATCCCGGCTTTAGGGGGCATCTCATTACCTCCAGGGG TCATCGTCATGACAGCCCTTCACTCCCCCGCAGCAGCCTCAGCAGCCGTCACAGACAGTGCGTTTCAAAT TGCCAATCTGGCAGACTGCCCGCAGAATCATTCCTCCTCCTCCTCGTCCTCCTCGGGGGGAGCTGGCGGA GCCAACCCGGCCAAGAAGAAGAGGAAAAGGTGTGGGGTCTGCGTGCCCTGCAAGAGGCTCATCAACTGTG GCGTCTGCAGCAGTTGCAGGAACCGCAAAACGGGACACCAGATCTGCAAATTTAGAAAATGTGAAGAGCT AAAGAAAAAACCTGGCACTTCGCTAGAGAGAACACCTGTTCCCAGCGCTGAAGCGTTCCGATGGTTCTTT TAAAGCTGTAGTGTATCTTATTTTCAAGGCATTTGGGAATGAAGGGCAAACTAATGTCTTGTTTTAAGAA ACCGCTTAGTCCACCATTGAAGAAATTATCCAGAAATTATTTTCATTTTATGTATAGGGATTTCTTCAAA AAAAATCAAAAAACAAAAAACAAGAGGAAAAGAAAACACCAACAGCAACAACAAAAAAAAGACACATAAA ATTAACAGGGAAGTTTGGGGAATTGGCCAGTTTATTTACTTTCAATACACTGATTCTTCCTTTGATGTAT TTAGCTCTACTAGTGAAGTTGTTGTCTATTTTGAAAGTGGCTGTAAAAAAAAATAATAATAATAAGTTTG GGTAACCCCCGACTGTAAAATCATGTATCTTTGCAAAGTACATATCTATACTTCATTTTCAAATATATGT GTTTCAGTACTGTAAACTGTACAGATAGCAGCTTGTATTTTGTGTGTTTAGACACAAGGAGACAATCATG TCTGAGCATCTATGGAGATTAACAGTTTGTACACAACACTATGGTTCTGCAAGTTAAAAATCTGGAGCAA TAAATTTTAGCTTTAAATATTTTTTGGCCAGTTGTTTTTAGAAGCAGAAACAACACCGGCGGGTGGTTTT CATGCATCTTTGTGTAGAGGCTTGTTGGCTGGTTTGTCAAGACTAAAAGATAATGCCGCATCCAGCAATG ACCTTCGGTTGTGTTGATATAAGAGGGAAAGCTACAATGAAGGTTGCAATTAATCTTTTGAGCACTGTAT TAGAGTAGTGGTTATGCACTTGCATTGCTTACAAACGAGCTGTACAGAGGGGATACCCCCGGATATTTAG TGTAGTTGACATGTTTGGGTTGCACTGTAAGGGGAGTACGCTGAATAGTTGGAAAATGCAGATTCAGTTC TATCTTTTTTAATTTTTTTTAATTGAAAATGTGTTTTCTAGGCTAACCTTATCAGATCATAGAAAGACAA ATTCATGCCTGACACCACTTTTTTCCCCTAGGCATACACAGGTTGTTTAAGCTTTTTTATTCTTTGATTA TTATTTTGCTTTGGGGAAGGGTAAGAAAAACAAAAACCAGAGAGTATTCAAAATGTTTGAATTCTGTGTA TGACGCTGGATGGGTAGGTTTAAAACAATGCTCAAATGCATTGAAGCCTACTTTAAGGCATGACTGGGCT TATTTTCAAGTTCAAAATAATCAAGCACATTGGTTAAAAGGGAGGCTTTTTTTTTTTGTTTCTTTATCTT CCTTTCCTTAGTCTCTCAGTTGGACCACTATTCTTCCCCAGTCTCTCATGGAACACCCACTGCTTCCCTC CCCTTTCTTACCACTGGAAGCTTTCTTTTCACTGAAGCAAGGCCACAGTGTGAGGAATTTCATAAAAACA AGACAGCCCATCCCCCACTCCCACCTCAGAATGCTTTATAGAACCAGGGCTGCCTCACCCTGTACGAGTT GGTTTGCCTAGAACAGTCTTGCTTCTCAAAGGATGCCCATCCCAATAAGACAACTAGCCTAAAAGAATCA GTTTCAGGAATAAAACATAGTTTAGGAAAGACACAAAGAATAACAAAGTTGCCGCGTCACTTACCTCTTT GTTCTTTATGACCACCAGACAGGTTAGCCAGCTGAATCAAAAGGAAAGCAACAGGAGAGATCGATAAGTC AGCCAAGACTTTAGAGTCTAAAGGGCTTCAAAAGCTGACAGGGGAATATTTTAAAAATTTCATTTTAGAT TTGAATGGAAAGAGGGATGACATTTTTTTTTTTCTAAAGGCAGGTCAAATACTACGCCATCATTGGTCAT CTGGATGAGAGTATAGTAGGTTTGTAGGACGCAAGTGTAAGGCACCAGTGGGACGAATGTGCCTGGCTAG CATACCAGTGCTTAGTCTGCAGTATGGTCAAGCAGCGTTTGTGAGGAAAATGTATTATGTATTACACCTG CCTATGCTTAAAAAGAGGGATGAACTCATCAAAAGGTAAAATGTGCTGTGTATTACTTTTGAGATAGCAT TCTCCTCCGTGTGAATTCCCTAGACTGTTTGAAGCTATAATTTCTGTTTCTGCTGTAGGACCAATGAGAG TTCTATGATTTCTTTATTTCTTTATTGTCCCACTGTCTGTCTGCCTGTCTGTCTGTCTCTTTACAATTTT TACTTTATTATTTTATTTTATTCTTATTTTGGACAATTTGTTAGTGAACTATGAGCACGTGAAAATTTAT TTTCACACTTGAATGGGACGCTTCCCTTGCTTATGTTAAGAAAAAAAATGATTATAAATGAAACCAATTT CCTTTCAGACTGTATTAGGCACACAATAAGGACCTCATAGCAATGTATGGAAAGTCAAAAACTCAAGGTG GTATTGCATATCTTGATATATTTTTCTGTTTGTTTGTTTGTTTGTTTTTTGGCTTTTGTTCTAAGACAAT GAATTTGTGTATTGTAAATGTGTTGTTTCACATGGCTGTCCATTTATTTTTAAGTAGAGGAATCTGTTTG TTACCATGATGAACAGTGTGGCCTTTTTTCTTTAATTTTTTTTTTTTGCATTTTCATTATTAACACTAAT TGCTCTTATGCCACACACTTCTTATGTTTCCTCTTAAACTCAGTTTACAAAATGTAGGGTACAGATAGAG TTCTCACTGGTGATGGTGAAGAAATGAGCCTTCTACATTACCTCTAGTTTTCTTTCTCAAGTTTATCTAC ATACCAACAGCCTGTAGCCTTAGGGCAGTGAAGGGATGCCTGTGTATTTTCTTTATTTCAAAAATGTAAA TGAAACATAACTTTTAACAGCGGCTCACTGTGTGTCTCATTTTCCATACCAAGGAAATTTAGAAGTTAGC AATCAGATTGTAGGTCGTATATATACAACTTAAAACTGACATGCCAGACCAGATGTTGCTCAAGCTGCTG GAGAAGTCCACGTACACAAGAGTCCAGTCTTCACGGATGCCATTCCCTGGCAGCATTTGAGGGGAGTACA GGAGAACATGTGGGCCGTTGGCACATAGTGTGTTTTGCAGATGCTCCATCTAGCTATTCCTTAGCACACC AGAAGAATATTATAATGCAGAGCTCTGTCTTTATTGACTTTCAGACTAAAGTGACTTTCTGTTGGACTCC TCTTCTCCTCATACAAACACAGAGGCCCACTCACAAAGTAGTACTGACTCCATCCAGATTACATGAATAG TAAATATCTTCCCCTAATGTATGGGTATGCAAAAACGTCTCCTGTTTTGTTTAACCCCAAACCTTCCATT TCATACTAAGCAATCACAGGGAGTGAGAGACAATGGGCTTGTTATGAATTAACATTAAGTAATCATGAAA GGAATGGAATGTTCCATCCTTTGTCAGAAGCCCTGGTGTGGATGTTGTTCAATTAGTGCTAAAGCATAGA AAGACTAGCTGATTGTATCAGTAATCAAAGAAAGAAAATAGAGACACAGTTAAATGAAGGCACGAGTCAG GGTCAAATATGTTGAGCAGAAAGCTGTAGTGGGTCTTTGATCATGGTGAGATTCACAGCGATATCAAACA GTTGGTTCTCATGTAACAGCTAAATGTTTCAGATTTTGTTTTTTATTAAATTTGACATTTCACACTGAGA TCTGTATTCCTAGCGAGTAGAACACAGCTCCTGTGTTCAGAGGGATTCCGTTCCACAATTGACAAATAGA TATTTCAGGACATGGGCCACCAAGTGTACTCCGTTCCCAGTGTCCTCCCGTTCTGAACTGTGCAGTTATC GGTTACATTTTCTAATAGATATTTGTGTAAAAGTGTATGTAAGCTTGTGCAGTTATTTTAAAAAGCAGTT TTGGAAAACAGTGTATTTATTAAAGAAAAAATCACTTATGGGGCATGTACAAAACTGTAAAAAAAATTAA AAATCACTTCAATTTGCCCAGTAAAGTTGTTTTTGTGAGATTTCTGTGTTGTTAAATAAAGGACTTTAGT ACTCAAAAAAAAAAAAAAAAAA
Notes:	The probe template was PCR amplified from IMAGE:30537505 using vector (pYX-Asc) specific primers. Forward Primer - name:RZPD T3, sequence:ATTAACCCTCACTAAAGGGA; Reverse Primer - name:RZPD T7, sequence:TAATACGACTCACTATAGGG. Anti-sense probe was then transcribed from the PCR amplified template using T7 polymerase. EMAGE Editor's Note: the probe sequence indicated here was given by the EURExpress Consortium and has been checked using a computational method whereby a BLAST comparison was made against the full insert sequence of IMAGE:30537505 which was retrieved directly from NCBI.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	C57BL/6
Age:	14.5 dpc
Theiler Stage:	TS23
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	none
Embedding:	cryosection (OCT)
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Dr. Graciana Diez-Roux, Prof. Gregor Eichele, Prof. Richard Baldock, Dr. Duncan Davidson, Prof. Stylianos Antonarakis, Dr. Marie Laure Yaspo, Prof. Salvador Martinez Perez, Dr. Pascal Dolle, Dr. David Tannahill, Prof. Pier Paolo Di Fiore, Mr. Stefan Kruse, Mr. Paolo Sarmientos, Dr. Uwe Radelof, Prof. Andrea Ballabio.
Principal investigator:	Professor Andrea Ballabio, Fondazione Telethon, TIGEM Instituto di Genetica e Medicina, Via Pietro Castellino 111 80131, Napoli, Italy 80131
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	screen
References:	[ doi:10.1371/journal.pbio.1000582] [ PMID:21267068] Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, et al 2011 A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo PLoS Biol (9)
Links:	EMAGE:12067 same embryo
	EMAGE:12070 same embryo
	EMAGE:12069 same embryo
	EMAGE:12068 same embryo
	EMAGE:12072 same embryo
	EurExpress:euxassay_008607 same experiment
	MGI:4824141 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source