EMAGE mouse gene expression spatial database

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EMAGE:11591

Ldoc1l leucine zipper, down-regulated in cancer 1-like ( MGI:2675858)
TS23 (14.5 dpc)
in situ hybridisation

Data Images


"Pseudo-wholemount" of euxassay_006988. This image has been made by aligning and collapsing the constitutent sections. Information about the method.	euxassay_006988_01	euxassay_006988_02	euxassay_006988_03	euxassay_006988_04

euxassay_006988_05	euxassay_006988_06	euxassay_006988_07	euxassay_006988_08	euxassay_006988_09

euxassay_006988_10	euxassay_006988_11	euxassay_006988_12	euxassay_006988_13	euxassay_006988_14

euxassay_006988_15	euxassay_006988_16	euxassay_006988_17	euxassay_006988_18	euxassay_006988_19

euxassay_006988_20	euxassay_006988_21	euxassay_006988_22	euxassay_006988_23	euxassay_006988_24

View assay images:
Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

11591_wholemount_strong.wlz

11591_wholemount_moderate.wlz

11591_wholemount_weak.wlz

11591_wholemount_possible.wlz

11591_wholemount_not_detected.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:11591_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

brain

moderate

regional

moderate expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24

facial vii ganglion

moderate

regional

moderate expression: see section 05 20 21 22

glossopharyngeal ix ganglion

moderate

regional

moderate expression: see section 07 18 19

trigeminal v ganglion

moderate

regional

moderate expression: see section 03 04 05 06 07 08 17 18 19 20 21 22 23

vagus x ganglion

moderate

regional

moderate expression: see section 08 18

vestibulocochlear viii ganglion

moderate

regional

moderate expression: see section 06 07 08 18 19

trigeminal v nerve

moderate

regional

moderate expression: see section 09 17

spinal cord

moderate

regional

moderate expression: see section 09 10 11 12 13 14 15 16 17 18

dorsal root ganglion

moderate

regional

moderate expression: see section 08 09 10 11 12 13 16 17 18 19

neural retina

moderate

regional

moderate expression: see section 01 02 03 23 24

nasal cavity olfactory epithelium

moderate

regional

moderate expression: see section 08 09 10 11 12 13 15 16 17 18 19

metanephros

moderate

regional

moderate expression: see section 08 09 10 11 18 19 20 21

left lung

moderate

regional

moderate expression: see section 04 05 06 07 08 09 10 11 12 13 14

right lung

moderate

regional

moderate expression: see section 15 16 17 18 19 20 21 22 23 24

Annotation Validation:

spatial mapping by EMAGE editor, text annotation by author

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	T9153
Entity Detected:	Ldoc1l, leucine zipper, down-regulated in cancer 1-like ( MGI:2675858)
Sequence:	sense strand is shown >T9153 GCGGTCTCTATGGCAACCAGCAGGCCCTGGCCCAGTTGCCAGGTTCCCAGCGGCCGTCTAGCTGGCCGCG CCTGCACAAAGACCGCGCGGTGACCGCGCAGCGCAGCGCCGGGACCAGGTCAAGCCAGCCCCGCAGGAAT TGCCACCCCCGCCGCCGCTGCCCGGAAAGCAGTTCCGGCGGCCTCCGTGACGTACAGGCCGGGCGCGGCC TCGACCCTCGGGCCATCTTGGCAGCGGAGGGAGCAGCGGAGCGACAGGTACATACGCCGCCCAGCCTGGG CCAGCCCAGGTGCCGACGCCTTTGTTCACGCGCGGGTGGTCGCATGGCACCGGTGGTCAGTGCCTGCATC CGCAGCCCGAGCTCCGGCAGGTGCATCCTGCAAAGTCTGGCAGGTCCGCGCATCTCGTAAGGCCTGGGCA GATCCAGCCTATGCATTCTACAAGGGCTATCCAGCTCGAGCATCCTTCAGGGCCTGGGCAGGTCCAGCCA GCGACCCACACTTTGATCCTGCGAAGCTTGCAGAAAGGAACTGCATCCAGGACAGGACCAGCGTCCTCAG GCTTGCTTCAGCATCCAAGGCCTTGCGCTCTGGTTCTCCAGGTACCTGTGGCTTAACTTTGGCCGCCAGC ATGGTCCAACCTCGGACCTCCAAAACTGAAAGCCCAGCCTCTGCCCCTGGTGCCAGCGCTCAGATGGATG ACGTAGTTGACACCCTGACCTCTCTGCGCCTCACCAACTCCGCGCTGAGGCGCGAGGCCTCCACACTGAG GGCGGAGAAGGCCAACCTCACCAACATGCTGGAGAGTGTGATGGCCGAACTAACTCTGCTGCGCACCCGA GCGCGCATCCCTGGCGCTCTACAGATTACTCCACCTATCTCTGCCATCACCTCCAATGGGACCCGACCCA TGACCACGCCACCCACCTCACTGCCTGAACCCTTCTCAGGAGACCCTGGACAGTTGGCAGGGTTCCTGAT GCAGATGGACAGGTTCATGATTTTTCAAGCCTCCCGCTTCCCCGGTGAAGCCGAGAGAGTGGCCTTCCTG GTATCCCGTCTGACTGGGGAGGCGGAGAAGTGGGCCATCCCCCACATGCAACCAGACAGCCCTTTGCGAA ACAATTACCAGGGGTTTCTGGCTGAGCTCCGCAGAACCTACAAGTCCCCGCTGAGGCACTCAAGGCGAGC ACAAATCCGGAAGACATCCGCGTCCAATAGGGCTGTGCGGGAGCGAGAGCGGGAGCGCCAGATGTTGTGT CGCCAACTGGCCGCAGCTGGCACAGGATCCTGCCCGGTGCATCCAGCCTCCAACGGGACCAATCCCGCAC CAGCCTTGCCCTCTCGTGGCCGGAACCTTTAAGGACTTGCCACCACCCTGGTAGTCTGTGTCCACCCAGG TAGCTAGACTCCGTTGTTGAGAGTTGTCAATTCAGTAGCTTTGCCCTGTTTGAGGCACCCTTCACGCCTC TCTGGTCTACGGGAGACCATCCTGTCATCGGCATTGGTCACCCACCCCGCTGTGCGGCGTGTATTTGTTT TGTTAGCGTTACCCGCGACTCAGTGCATGCTCCCCCTTTCTGTTGCTTGCAATCCCAGCTTCTCCAGCAA TCACAACACAGCCCCTTGGGCATGTGCCTGCCCAGGAACCATTTAGGCTGACCACCTCTGCGAGCTCAGC TCACGGATACTCAGCTCCTGGAACACTCCCTACAGCTCTTGCTGCCCCAGGCTGAAGAACTGGCGAGGAG TGGCCAACTGCTTCGGGTCTCATGTGGACACATGTTCCAGTCCCAAGGAGCAGAGCCTCACAGGAGGATG ACCTCTCAATCAGACTCAGCCAAGCCTCTGGACCATGACATCATCTGTCATTTCAATGCCAAATGAACTG TGTTTACATACCTACCTGGCCCCTTTGGGGAGATGGGTTACCTCTCCTGGGTTTTCCTGCCCTCCTCTGC ATGGTCTTGGCTTGACCACAAGAAAACCAACAACAACAACAAAACCGCCTCTGAACCCACGGAAAGACAT CTCTCTCCTCTCAGGAGCCCAGAGGCTGGGGCCTAGAACCCGGCCTCTTCCAGAGACTTTCTCCGTCATT GGGAAAAGTGACTGACTAACCAGCACAGCCACCTTTGCAAGACCAGGACAGGAGTCTTCGCTGCTCGCTG GGCTCCCGGCCCATAGCCACCTGCTTCTTGTTAACTCTGTTAGCCTAGCAGCCTCACTGAACAGCCAGGG CACCCTGCTGGCACTATGGTGCTATAAGCAGGTGGAAGACTCCTGGGGTTCCACTGAGAGTACTCACCTA TCCCCAGCAGCTGAGTCTCATGCATGACCTTTCGGTGGAGGGGTCCCCAGGTGAAGCTACAGCTGCACCA GAAAAAATGGGGGATAGGGAGGAGGTGTATGTGGAGGCAGGTGACAACTGGAAGGTTTCTTTGTGGCTTT CCACGTTGTTGTCGAGGCCCATCCACCGGGGAGGCAGGTCACCTGCCCTGGCTCCTCGGACCAATGGGTG CTGGCTGTATTTGCATTAGGTTTTGCTTCAGAGCCATTCAGGCTGCCTGTCTCCAGGTGTGGCTTCATTA CCTTCTGCTGCATCTGGTTTGACCCACCTGGGCCACTCTGCCTCAGTGGCTCCGTCCCTACCTCTGCTCT GGTGGTGGTGGCTTGGCAATGGTTTTGTTTCTTGATGCATGTATTTAGGACCGACATCTCAATAGCTCTC TGTGGCTTGGAGCCTGGAGCACACAAGAGAGGGTTGAGGCTTGCCCTCTGCGTCGGACCTGGAAGAGACA CTTGGGATTGGTTGCTGAGGGGCCCATGGTGGCTCTCGTCGGGGCCGTGGTTTGTCCCCAGCCAAGACGA TGAGGTGCAAGGCCCATGTAGCTCCAGAGGGAGACTGTGATAACTGGACCTAAAGCTGAGCAAGAGGGGG AGGCTTTGTACATATCTTAAGGTTCTAGTTGCTTGAGCTCAGAAGAGAACAGGGAGAGGGGAATGGGGGA GTTGGTCTATGAAGGAGTTGTGTCACTCCACATTGACAGTCGCGGCGGTACTGTGCCCGCTCTCCAGACT CTGTGACACCCATCCGGTAGGTGGGGCTTCACTGTACTCAGCGTCTAATGGACAGGGGGACCTGGCATTT GGGTGACTTCCCAGCCCAATGTTTACTGTGATCTTGGAATTATCTCCATGTCCCAAAGCATTCAGTGACT TTGAGGAAACAGCAAAGATCCATCTCCTTATCCCTGGCTAAATCCATGACAGGGTGCGCATGCTCTGTAT GACAGGGTGCGCATGCTCTGTGTTAGGGCATCTGGGCGGGCCTGAGATAGATGCCTGTTGCTGCAGAGGA CAGAGCCACTTCTGGATGTGCATGCCCTGGGCTTCAGCTTGCAGGGGAGTGAATGGCAGTGGAGAAGTTG GCATAGGCATAGCGTGACTTAGGGAGCAAGCCTGGGGCTTAGCTGGAACACACTGGGGACAGGGTGTTGG GTGGCAAATGCTCGGCTGCGTAGCCTGAGTGCTAAGGCCATCCTGTGGCCCTTTGCCTGGGAGATGTCCG TCAGGAGCTTTGCTAGGACACCGTGAAATGAGGCTCGGGTTAGGGAGTGAGATCTGGAGCTTGGACAGGC AGGCAAGCTTGCAGTGTCTGGGAGGTCCTCGCCTTTGGCATCTCTCTAGGACCTCATGTTGGACTCGGTG GCAGCCAGTGGAGCTAAAGAGAGGCGTCCCCACCCAGTGCCATCAACATGTGGACCAGGGCTTCCCATTC TCTACAGCAGCAGACCAGGAATTCTGGGGGACCAGGGAGGGGAAAGGAAAATGGTAAAATTCAATGTTTT GATGTTTCCTTCCTGTCCCTGGCCTGGAATTTCTTTGCCTCTTATACAGCCATGGTGCTGCCTGTGGACC CCTACTGTGTACATATGACAACACTGTTTCCATGTGCCACCCACCTTACCCTGAGTGACTGTGAACCCTC CCCTCAGGCAAAGGAACAGTGCTGGTACTGTCAGATACTGACAATGTGTCAGGTTTTCCTCCAAGAAAGG AGCCAAAGTTGCTTCCTCGGGATTCGTTCTCTAAGGTAGGATTATTGGATTAGTGAACATGGGGCCCTCT GAGACTTTTACTACCTACAGACAAAACGGTTTCCAGAAGTTTCAGTGTCCATTGCACGGCCCCCATCGAG GGGAAGTGTCCTGGTTGAGGGTCTTCTCCCAGGCCCGAGGACTCCCTGACTTGGCGAGGTCAGCCGCACC ATGTTTTAGTTGCATCTTTCGATCCTAGCTCACCGTGAGTCGTTTCACACCAAGTGACTGCATTTCCTCT TTTGCAGACTGCCGCTGTCCTTTGCCCCACTGACGGGCCTGACCAGTTTGTAAGAGCTCCATATGTAATT AAAGATACTAACCTGGAAAAAAAAAAAAAAAAAAAAA
Notes:	The probe template was PCR amplified from IMAGE:6826763 using vector (pYX-Asc) specific primers. Forward Primer - name:RZPD T3, sequence:ATTAACCCTCACTAAAGGGA; Reverse Primer - name:RZPD T7, sequence:TAATACGACTCACTATAGGG. Anti-sense probe was then transcribed from the PCR amplified template using T7 polymerase. EMAGE Editor's Note: the probe sequence indicated here was given by the EURExpress Consortium and has been checked using a computational method whereby a BLAST comparison was made against the full insert sequence of IMAGE:6826763 which was retrieved directly from NCBI.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	C57BL/6
Age:	14.5 dpc
Theiler Stage:	TS23
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	none
Embedding:	cryosection (OCT)
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Dr. Graciana Diez-Roux, Prof. Gregor Eichele, Prof. Richard Baldock, Dr. Duncan Davidson, Prof. Stylianos Antonarakis, Dr. Marie Laure Yaspo, Prof. Salvador Martinez Perez, Dr. Pascal Dolle, Dr. David Tannahill, Prof. Pier Paolo Di Fiore, Mr. Stefan Kruse, Mr. Paolo Sarmientos, Dr. Uwe Radelof, Prof. Andrea Ballabio.
Principal investigator:	Professor Andrea Ballabio, Fondazione Telethon, TIGEM Instituto di Genetica e Medicina, Via Pietro Castellino 111 80131, Napoli, Italy 80131
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	screen
References:	[ doi:10.1371/journal.pbio.1000582] [ PMID:21267068] Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, et al 2011 A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo PLoS Biol (9)
Links:	EMAGE:11593 same embryo
	EMAGE:11592 same embryo
	EMAGE:11594 same embryo
	EMAGE:11595 same embryo
	EurExpress:euxassay_006988 same experiment
	MGI:4825895 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source