EMAGE mouse gene expression spatial database

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EMAGE:7711

Wbscr17 Williams-Beuren syndrome chromosome region 17 homolog (human) ( MGI:2137594)
TS23 (14.5 dpc)
in situ hybridisation

Data Images


"Pseudo-wholemount" of euxassay_007480. This image has been made by aligning and collapsing the constitutent sections. Information about the method.	euxassay_007480_01	euxassay_007480_02	euxassay_007480_03	euxassay_007480_04

euxassay_007480_05	euxassay_007480_06	euxassay_007480_07	euxassay_007480_08	euxassay_007480_09

euxassay_007480_10	euxassay_007480_11	euxassay_007480_12	euxassay_007480_13	euxassay_007480_14

euxassay_007480_15	euxassay_007480_16	euxassay_007480_17	euxassay_007480_18	euxassay_007480_19

euxassay_007480_20	euxassay_007480_21	euxassay_007480_22	euxassay_007480_23	euxassay_007480_24

View assay images:
Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

7711_wholemount_strong.wlz

7711_wholemount_moderate.wlz

7711_wholemount_weak.wlz

7711_wholemount_possible.wlz

7711_wholemount_not_detected.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:7711_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

anterior abdominal wall musculature

moderate

regional

moderate expression: see section 01 weak expression: see section 02 03 04 05 06 17 21 22 23

axial musculature

moderate

regional

moderate expression: see section 01 02 03 04 05 06 21 22 weak expression: see section 07 17 18 19 20 23 24

diencephalon

moderate

single cell

moderate expression: see section 07 08 09 13 14 17

cerebral cortex mantle layer

strong

regional

strong expression: see section 05 06 07 08 13 14 15 17 21 moderate expression: see section 01 02 03 04 09 10 11 16 18 19 20 22 23 24

telencephalon mantle layer

moderate

regional

moderate expression: see section 01 05 06 21 22 23 24

hindbrain

moderate

single cell

moderate expression: see section 06 07 08 09 10 11 13 14 16 17 18 19

midbrain

moderate

single cell

moderate expression: see section 06 07 08 09 11 13 14 19

facial vii ganglion

strong

single cell

strong expression: see section 05 21 22

glossopharyngeal ix ganglion

moderate

single cell

moderate expression: see section 07 08 19

trigeminal v ganglion

strong

single cell

strong expression: see section 04 05 06 07 08 09 18 19 21 22 23 moderate expression: see section 20

vestibulocochlear viii ganglion

moderate

single cell

moderate expression: see section 07

dorsal grey horn

moderate

regional

moderate expression: see section 13 14 weak expression: see section 10 11 12 15

ventral grey horn

moderate

regional

moderate expression: see section 13 14 16 weak expression: see section 11 15

dorsal root ganglion

strong

single cell

strong expression: see section 15 16 17 moderate expression: see section 08 09 10 13 14 18 19

Annotation Validation:

spatial mapping by EMAGE editor, text annotation by author

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	T8971
Entity Detected:	Wbscr17, Williams-Beuren syndrome chromosome region 17 homolog (human) ( MGI:2137594)
Sequence:	sense strand is shown >T8971 TACAGGGAGAGACCCTGGGACCTTTATCTTTTGCTGTCTTGTAGAAGGGACTGCGTGCTGTGGACGGAGC AGGCATTTCAGAGACACTTTTGCAAGCCAGGGGCTTCCATGTGAGAGATCAGCCGCGTCCTTCCAGTGGT TACTGGCGCCAGAGAATCGGCGTTTTGTGGTCAACAGCAGCTGGGACCCCCAGCCCTTTGCCCCCTCCCT CGGCCATTGTTCGGTGTGTGGGGTCTACTCCGTCTCAGGCTGCCCTGCGCCTCGCAGGTGAGGCTGGTAG AGGCGTGGGTCCAGGGAAAGGACCGGCCGTGTTGTTTGATGGCTTCACTGAGGAGAGTCAAAGTGTTGTT GGTGTTGAACTTGATCGCGGTGGCCGGCTTCGTGATCTTTTTGGCTAAGTGTCGGCCTATCGCGGTGCGC AGCGGAGACGCCTTCCACGAGATCCGGCCTCGCGCAGAGGTGGCCAACCTCAGCGCGCACAGCGCCAGCC CCATCCAGGATGCGGTCCTGAAGCGCTTGTCGCTGCTGGAGGACATCGTCTACAGGCAGCTTAATGGCTT ATCTAAATCCCTCGGGCTCATCGAAGGGTATGGTGGGAGGGGCAAAGGAGGCCTTCCTGCCACCCTTTCC CCCTCTGAAGAAGAAAAAGCCAAAGGACCTCATGAGAAATATGGCTACAATTCCTACCTCAGTGAAAAGA TCTCCTTGGACCGGTCTATTCCAGATTATCGTCCTACCAAGTGTAAGGAGCTCAAATATTCCAAGGAGTT GCCCCAGATATCCATCATCTTCATCTTCGTGAATGAGGCCCTGTCTGTGATACTTCGGTCAGTCCACAGC GCTGTCAATCACACACCCACACACCTGCTGAAGGAGATCATCCTGGTGGATGACAACAGTGATGAAGAGG AGCTGAAGGCCCCCTTGGAAGAGTACGTCCACAAACGCTACCCTGGGCTGGTGAAGGTGGTACGCAATCA AAAGCGAGAAGGCCTGATCCGAGCACGCATCGAGGGCTGGAAAGCGGCCACTGGCCAGGTCACTGGCTTT TTCGATGCTCACGTGGAATTCACTGCTGGCTGGGCTGAGCCCGTTCTGTCCCGCATCCAGGAAAACCGGA AGCGGGTCATCCTCCCCTCCATCGACAACATCAAGCAGGACAACTTCGAAGTGCAGCGCTACGAGAACTC CGCCCACGGGTACAGCTGGGAGCTGTGGTGCATGTACATCAGCCCCCCAAAAGACTGGTGGGACGCCGGA GATCCCTCTCTCCCCATCAGAACACCAGCCATGATTGGCTGCTCATTTGTGGTCAACAGGAAATTCTTTG GTGAAATTGGTCTGCTGGACCCTGGAATGGATGTGTACGGAGGAGAGAATATTGAACTTGGGATCAAGGT ATGGCTCTGTGGTGGCAGCATGGAGGTCCTTCCATGTTCAAGGGTGGCCCACATTGAGCGGAAGAAGAAA CCGTATAACAGTAACATCGGCTTTTACACCAAGAGGAATGCATTGCGAGTAGCCGAGGTCTGGATGGACG ACTACAAGTCACATGTGTACATAGCGTGGAATCTGCCTCTGGAGAATCCAGGCATCGATATCGGTGATGT CTCAGAAAGAAAAGCATTAAGGAAAAGTTTGAAATGTAAGAATTTCCAGTGGTATTTGGACCATGTTTAC CCAGAAATGAGAAGATACAACAACACTATCGCCTATGGGGAGCTTCGTAATAATAAGGCCAAGGACGTCT GTCTGGACCAGGGGCCACTGGAAAACCACACAGCAATACTGTACCCATGCCACGGTTGGGGACCACAGCT CGCCCGCTACACCAAGGAAGGGTTCCTGCACTTAGGTGCTCTGGGGACCACCACTCTCCTCCCTGATACC CGCTGCCTGGTGGACAACTCCAAGAGTCGGTTGCCGCAGCTCCTGGATTGTGACAAGGTCAAGAGCAGCT TGTACAAGCGTTGGAACTTCATCCAGAATGGAGCCATCATGAATAAGGGCACAGGGCGCTGCCTAGAGGT GGAGAACCGGGGCCTGGCCGGCATCGACCTAATCCTTCGAAGCTGTACTGGACAGAGATGGGCAATCAAG AATCCCATCAAGTAGATGGACAGAAGGAGGGCACATGGAGCCCAGACCCAGGGCAGGGCCTGGCCATCCT CAGAAGCAGCCACATGGTGGAGAGACAGCAGGCACCCAGAGGATGCTCTGTGGACCTCTCAGGGCTCCTC CAGAGCAGCCCTGGATAAAGATGTTACGTCCCCCTCAGGCATTCTGCCTGTGTACTTTGAAGATCTTCCC CTTATTCTCATCTGGGGACCAGGGGCTACAACTTCTGGGTACTAATGGGTGAGGCTGCTCATATCTCTCC ACGGTATCATCTCCCACCCCAGCATCAGCAGCTGGGTTCTGGCAGGGTCCCTCTCCCTCCCTCCCCCCTC CCTTCCTTCCTTCCTCTCTCCCTCCTTCCCTCCCTCTCTCCCTCCCTCCCTCCCTCTCCACTCTTTTCTC TCATCCTTTGCTGCAACTACTTGTGTAACTCACCCTGGACCTCCAAGACATGGAGGACAATGAGGGCTTT AGCCACATCCTAGCTCCTCCCTCTTGGAGAAGGAAGCAGTAAGACTCCCAAGACTCCATTTCTCCTTAAG ACACTTTGCCCCAGAGGCCTGTTTGTATGCCAAGGCAGCAGCCACTCAGACCTTCTCTGCAAGGTGACTT TGAGACAAGAGTTCTGGACTCCTCTGGATTGTTCTTGAGGTTCCCTGTCCCAGTCACCCAAAGCCCTAAA TATGGACAGCATCAGCGCTTGAGCCTGTGTCTAGAGGGAGCTGGAAGTCAGCTGCTCATGCTGGATGCTC CTAGCACCTGGCTAGTACAGCAGCTCTGCCTGCCAAGGACAAGGTGCCCTGGTTTCATGGAGCAGCAAGG GTCTTCCATGCAGGACATAAGGGCTGAAGAGTCAGCCTAGTGATGGGCACAGGGCCCTCTGTGACGCTTA CTGCTCAGCTCATTTCACCCCATGCTTTGCTGGCTGATGGGGGACAGAAGCGGCCATTTCCTCTTTTAAG AGTGATTGCTTCTTTCCAATTGCCCTCTGGTTAGGGTGCACTTATAAATCAGAGTTAATATATGGATGTG TCTGCATGCACGGGAAAGCAAGAGTGTGCCTGCCTGAGTGATGTGTGTGGCTGGGTGTATGTTTGCGTGC TTGAGCGTGCGAGTGTGCTTGAGCAGTAGTCTCGGGCTTGTAGCTTCATTGCTCAGTGGATAGGGACAAG GACGCCTAGAAGAATGGGGGGTGGGAGGCATGTCCCTGGATCACGGGCCCAGAGGATATGTCTGGGTCTT ACATGCTAGGGTAACCTTTCTCTATCCCCTCCTCCAATCCACTACTGTCCTTGGCCATCTCCTGCCCAGA GCCAAACCCTGTAGGTGCCCAGTGTGGGATCCAGTATCTCATTTGGTGGTATCTTTATTGGTGATCATCT CCTTGCCCCATCTCCCCTCCTTGTGGAATAAATATGTTAGCAATCCCACAAAGCAAAAAAAAAAAAAAAA AAAAAAAAAA
Notes:	The probe template was PCR amplified from IMAGE:6810287 using vector (pYX-Asc) specific primers. Forward Primer - name:RZPD T3, sequence:ATTAACCCTCACTAAAGGGA; Reverse Primer - name:RZPD T7, sequence:TAATACGACTCACTATAGGG. Anti-sense probe was then transcribed from the PCR amplified template using T7 polymerase. EMAGE Editor's Note: the probe sequence indicated here was given by the EURExpress Consortium and has been checked using a computational method whereby a BLAST comparison was made against the full insert sequence of IMAGE:6810287 which was retrieved directly from NCBI.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	C57BL/6
Age:	14.5 dpc
Theiler Stage:	TS23
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	none
Embedding:	cryosection (OCT)
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Dr. Graciana Diez-Roux, Prof. Gregor Eichele, Prof. Richard Baldock, Dr. Duncan Davidson, Prof. Stylianos Antonarakis, Dr. Marie Laure Yaspo, Prof. Salvador Martinez Perez, Dr. Pascal Dolle, Dr. David Tannahill, Prof. Pier Paolo Di Fiore, Mr. Stefan Kruse, Mr. Paolo Sarmientos, Dr. Uwe Radelof, Prof. Andrea Ballabio.
Principal investigator:	Professor Andrea Ballabio, Fondazione Telethon, TIGEM Instituto di Genetica e Medicina, Via Pietro Castellino 111 80131, Napoli, Italy 80131
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	screen
References:	[ doi:10.1371/journal.pbio.1000582] [ PMID:21267068] Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, et al 2011 A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo PLoS Biol (9)
Links:	EMAGE:7714 same embryo
	EMAGE:7713 same embryo
	EMAGE:7712 same embryo
	EMAGE:7715 same embryo
	EMAGE:7716 same embryo
	EurExpress:euxassay_007480 same experiment
	MGI:4829189 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source