EMAGE mouse gene expression spatial database

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EMAGE:11652

Exo1 exonuclease 1 ( MGI:1349427)
TS23 (14.5 dpc)
in situ hybridisation

Data Images


"Pseudo-wholemount" of euxassay_008408. This image has been made by aligning and collapsing the constitutent sections. Information about the method.	euxassay_008408_01	euxassay_008408_02	euxassay_008408_03	euxassay_008408_04

euxassay_008408_05	euxassay_008408_06	euxassay_008408_07	euxassay_008408_08	euxassay_008408_09

euxassay_008408_10	euxassay_008408_11	euxassay_008408_12	euxassay_008408_13	euxassay_008408_14

euxassay_008408_15	euxassay_008408_16	euxassay_008408_17	euxassay_008408_18	euxassay_008408_19

euxassay_008408_20	euxassay_008408_21	euxassay_008408_22	euxassay_008408_23

View assay images:
Expression pattern clarity:
Find spatially similar wholemount expression patterns:

Expression Pattern Description

Spatial Annotation:

Annotation colour key:

	strong
	moderate
	weak
	possible
	not detected

wholemount mapping

Download individual expression domains:

11652_wholemount_strong.wlz

11652_wholemount_moderate.wlz

11652_wholemount_weak.wlz

11652_wholemount_possible.wlz

11652_wholemount_not_detected.wlz

(what is wlz format?)

Download all expression domains:

EMAGE:11652_all_domains.zip

Find spatially similar wholemount expression patterns:

EMAGE spatially similar wholemount patterns

Morphological match to the template:

Text Annotation:

Structure

Level

Pattern

Notes

upper arm muscle

moderate

regional

moderate expression: see section 01 02 03 04 05 06 22 23

upper leg muscle

moderate

regional

moderate expression: see section 01 02 03 04 05 06 07 08 09 20 21 22 23

forearm rest of mesenchyme

moderate

regional

moderate expression: see section 01 02

hand

moderate

regional

moderate expression: see section 01 02 03

foot

moderate

regional

moderate expression: see section 03 04 05 06 07 21 22 23

lower leg rest of mesenchyme

moderate

regional

moderate expression: see section 01 02 03 04

vertebral axis musculature

moderate

regional

moderate expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23

thymus primordium

strong

regional

strong expression: see section 11 12 13 14 15 16

submandibular gland primordium

strong

regional

strong expression: see section 07 08 09 10 17 18 19 20

pancreas

strong

regional

strong expression: see section 09 10 11 12 13 16 17 18

thyroid gland

strong

regional

strong expression: see section 10 11 12 15 16

vibrissa

strong

regional

strong expression: see section 04 05 06 07 08 19 20 21 22 23

diencephalon lateral wall mantle layer

strong

single cell

strong expression: see section 07 08 09 10 11 12 15 16 17 18

diencephalon lateral wall ventricular layer

strong

regional

strong expression: see section 11 12 13 14 15

telencephalon mantle layer

strong

single cell

strong expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 15 16 17 18 19 20 21 22 23

telencephalon ventricular layer

strong

regional

strong expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23

medulla oblongata alar plate mantle layer

strong

regional

strong expression: see section 12 13

medulla oblongata alar plate ventricular layer

strong

regional

strong expression: see section 06 07 08 09 10 12 13 14 15 16 17 18 19

medulla oblongata basal plate mantle layer

strong

regional

strong expression: see section 12 13

medulla oblongata basal plate ventricular layer

strong

regional

strong expression: see section 12 13 14

rest of cerebellum marginal layer

strong

regional

strong expression: see section 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22

rest of cerebellum ventricular layer

strong

regional

strong expression: see section 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22

pons mantle layer

strong

regional

strong expression: see section 13

pons ventricular layer

strong

regional

strong expression: see section 05 06 07 09 13 14 15 16 18 19 20 21

midbrain mantle layer

strong

single cell

strong expression: see section 07 08 09 10 11 12 15 16 17 18 19

midbrain ventricular layer

strong

regional

strong expression: see section 08 09 10 11 12 13 14 15 16 17 18

spinal cord mantle layer

strong

single cell

strong expression: see section 09 10 11 12 13 14 15 16

spinal cord ventricular layer

strong

regional

strong expression: see section 12 13 14 15

cornea

strong

regional

strong expression: see section 02 03 04 23

retina

strong

regional

strong expression: see section 01 02 03 04 23

anterior naris

strong

regional

strong expression: see section 12 13 14 15 16 17

external naris

strong

regional

strong expression: see section 12

nasal cavity olfactory epithelium

strong

regional

strong expression: see section 08 09 10 11 12 13 15 16 17 18 19 20 21

nasal septum

strong

regional

strong expression: see section 14

naso-lacrimal duct

strong

regional

strong expression: see section 03 04 05 06 07 08 09 18 19 20 21 22 23

vomeronasal organ

strong

regional

strong expression: see section 12 15

esophagus epithelium

strong

regional

strong expression: see section 13

tongue muscle

moderate

regional

moderate expression: see section 10 11 12 13 14 15 16 17

stomach

strong

regional

strong expression: see section 02 03 04 05 06 07 08 09 10 11

midgut

strong

regional

strong expression: see section 08 09 10 11 12 13 14 15 16 17 18 19 20 21

lower jaw incisor

strong

regional

strong expression: see section 11 12 13 15 16 17

lower jaw molar

strong

regional

strong expression: see section 06 07 08 19 20

upper jaw incisor

strong

regional

strong expression: see section 11 12 13 16 17

upper jaw molar

strong

regional

strong expression: see section 06 07 08 19 20

liver

strong

regional

strong expression: see section 01 02 03 04 05 06 07 08 09 10 11 12 13 14 15 16 17 18 19 20 21 22 23

bladder

moderate

regional

moderate expression: see section 13 14 15 16

metanephros

strong

regional

strong expression: see section 07 08 09 10 11 17 18 19 20 21

urethra of male

moderate

regional

moderate expression: see section 15

left lung

strong

regional

strong expression: see section 04 05 06 07 08 09 10 11 12

right lung

strong

regional

strong expression: see section 12 13 14 15 16 17 18 19 20 21 22 23

trachea

strong

regional

strong expression: see section 13 14

Annotation Validation:

spatial mapping by EMAGE editor, text annotation by author

Detection Reagent

Type:	in situ hybridisation probe
Identifier:	T6231
Entity Detected:	Exo1, exonuclease 1 ( MGI:1349427)
Sequence:	sense strand is shown >T6231 GGCTGCGCTTGCAGCAGCCGCTCGCCGCCGTTCTGAACCCCAGGTTTGAGGAGCCACGGCGCCTGGAATG GACTTGTGTGCTATGCCTGTTCGTTCGGGAGACGGGACTAAGTTAACTTGGCACGATGGGGATTCAAGGG TTACTTCAGTTCATCCAAGAAGCTTCTGAACCTGTCAACGTGAAGAAGTACAAAGGACAGGCAGTGGCTG TGGATACCTACTGTTGGCTTCACAAAGGGGCTATTGCTTGTGCTGAAAAGCTAGCCAAAGGGGAACCTAC AGATAGGTATGTAGGATTTTGTATGAAGTTTGTTAATATGCTGCTGTCTTATGGGGTCAAGCCGATTCTC ATATTTGACGGATGTACTCTACCTTCTAAAAAGGAAGTGGAGCGGTCTCGAAGAGAGAGACGACAAAGCA ACCTTCTTAAAGGGAAGCAGCTTCTTCGAGAGGGCAAAGTGTCAGAAGCCCGAGACTGCTTCGCTCGCTC TATCAACATCACGCACGCCATGGCCCACAAAGTAATAAAAGCTGCTCGGGCCCTAGGAGTGGATTGCCTC GTGGCTCCGTATGAAGCTGATGCTCAGTTGGCCTACCTTAACAAGGCTGGCATCGTGCAGGCTGTCATCA CAGAGGACTCTGACCTCCTCGCATTTGGCTGTAAGAAGGTGATTTTAAAAATGGATCAGTTTGGAAATGG ACTGGAAGTGGACCAGGCACGGCTAGGCATGTGCAAGCAGCTTGGGGATGTATTCACGGAGGAGAAGTTC CGGTACATGTGCATTCTGTCCGGCTGTGACTACCTCGCCTCCCTTCGTGGGATCGGCTTAGCCAAGGCCT GCAAAGTGCTGAGACTGGCCAATAACCCCGATATCGTGAAGGTTATCAAGAAAATTGGGCATTATCTCAG GATGAATATAACGGTGCCCGAGGATTACATCACAGGATTTATTCGTGCCAACAATACTTTCCTCTACCAG CTCGTGTTCGACCCCATCCAAAGGAAGCTGGTCCCTCTGAATGCCTACGGAGATGACGTTAATCCCGAAA CACTGACTTACGCTGGGCAGTACGTCGGTGACTCTGTAGCTCTTCAGATCGCCCTTGGAAATAGAGATGT AAATACTTTTGAACAGATTGATGACTACAGTCCAGACACCATGCCAGCCCACTCAAGAAGCCACAGCTGG AATGAGAAAGCAGGTCAGAAACCACCTGGTACCAACAGCATTTGGCACAAGAATTATTGTCCTAGACTTG AGGTGAACAGTGTCTCCCACGCTCCTCAACTGAAGGAAAAGCCAAGCACTTTGGGCCTTAAACAAGTGAT TAGTACTAAAGGGTTAAATCTTCCCAGGAAGTCTTGTGTGTTGAAAAGACCAAGAAATGAAGCGCTGGCT GAAGATGACCTGTTGAGCCAGTATTCGTCAGTTTCAAAGAAGATCAAGGAAAATGGCTGTGGGGATGGCA CATCACCTAACTCTTCTAAAATGTCCAAGTCCTGCCCCGATTCTGGGACTGCTCACAAGACAGATGCACA CACCCCGTCTAAGATGAGGAATAAATTTGCAACGTTCTTACAGAGGAGGAATGAAGAAAGCGGTGCAGTC GTGGTTCCAGGGACCAGAAGCAGGTTTTTTTGCAGTTCTCAGGATTTTGACAATTTCATACCAAAAAAAG AAAGCGGCCAGCCTCTAAATGAAACTGTGGCCACTGGCAAAGCCACCACCAGCCTCCTCGGGGCACTGGA CTGTCCAGACACGGAAGGCCACAAGCCGGTTGATGCAAATGGGACGCACAATCTGAGCTCTCAGATTCCA GGCAATGCAGCTGTGTCTCCTGAGGATGAGGCTCAGTCCTCTGAGACCAGCAAACTCTTGGGGGCCATGT CCCCACCCAGTCTGGGGACACTAAGAAGCTGTTTCAGTTGGTCTGGCACTCTCAGGGAATTTTCTCGAAC TCCAAGTCCCTCAGCAAGCACTACATTGCAGCAGTTCCGGAGAAAGAGCGACCCCCCTGCCTGTCTTCCT GAGGCCTCTGCCGTGGTCACTGACAGGTGCGACTCAAAGAGCGAGATGCTGGGTGAGACGTCTCAGCCCT TGCACGAGCTGGGCTGCTCCTCGCGGTCTCAGGAAAGCATGGACTCCTCGTGCGGCCTAAACACGTCGAG CCTGTCCCAGCCTTCCAGTAGGGATTCAGGTTCAGAGGAGTCGGATTGTAACAATAAGTCACTTGATAAT CAAGGGGAACAGAACTCCAAGCAACACTTACCTCACTTTTCAAAGAAAGACGGACTTAGACGGAACAAGG TTCCTGGGCTCTGTAGGTCTAGTTCTATGGACTCTTTTTCTACAACCAAGATCAAGCCCCTGGTGCCTGC CAGGGTCAGTGGCCTGAGCAAGAAGTCAGGAAGCATGCAGACGAGAAAACACCATGATGTGGAGAACAAG CCAGGCCTACAGACGAAGATCAGCGAGCTCTGGAAAAACTTTGGGTTTAAAAAAGATTCTGAAAAGCTTC CTTCTTGTAAGAAGCCCCTGTCTCCAGTCAAGGACAATATCCAACTCACTCCAGAGACAGAAGATGAGAT CTTTAACAAGCCCGAGTGTGTACGCGCTCAGAGAGCAATATTTCACTAAGTGCAGACCGTTGCCTACAAG AAAATCTTATCAACTGGAGAGATGTATTAGTCTCAATGTCATTTTTTAAATGGATTACATTTTGTATATT AACTTTGTGACTTTCTTTTGCTCAGCTTTTTATATTTTCATAGAAAGCTAAATAGAAGAATAAATCTGTC TTTGACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Notes:	The probe template was PCR amplified from IMAGE:3499406 using vector (pCMV-SPORT6) specific primers. Forward Primer - name:RZPD T7, sequence:TAATACGACTCACTATAGGG; Reverse Primer - name:RZPD sp6, sequence:ATTTAGGTGACACTATAG. Anti-sense probe was then transcribed from the PCR amplified template using Sp6 polymerase. EMAGE Editor's Note: the probe sequence indicated here was given by the EURExpress Consortium and has been checked using a computational method whereby a BLAST comparison was made against the full insert sequence of IMAGE:3499406 which was retrieved directly from NCBI.
Chemistry:	RNA
Strand:	antisense
Label:	digoxigenin

Specimen

Organism:	mouse
Strain:	C57BL/6
Age:	14.5 dpc
Theiler Stage:	TS23
Mutations:	none (wild-type)
Preparation:	section

Procedures

Fixation:	none
Embedding:	cryosection (OCT)
Staining procedure:	alkaline phosphatase + NBT/BCIP

General Information

Authors:	Dr. Graciana Diez-Roux, Prof. Gregor Eichele, Prof. Richard Baldock, Dr. Duncan Davidson, Prof. Stylianos Antonarakis, Dr. Marie Laure Yaspo, Prof. Salvador Martinez Perez, Dr. Pascal Dolle, Dr. David Tannahill, Prof. Pier Paolo Di Fiore, Mr. Stefan Kruse, Mr. Paolo Sarmientos, Dr. Uwe Radelof, Prof. Andrea Ballabio.
Principal investigator:	Professor Andrea Ballabio, Fondazione Telethon, TIGEM Instituto di Genetica e Medicina, Via Pietro Castellino 111 80131, Napoli, Italy 80131
Submitted by:	EMAGE EDITOR, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK EH4 2XU
Experiment type:	screen
References:	[ doi:10.1371/journal.pbio.1000582] [ PMID:21267068] Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, et al 2011 A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo PLoS Biol (9)
Links:	EMAGE:11650 same embryo
	EMAGE:11649 same embryo
	EMAGE:11648 same embryo
	EMAGE:11651 same embryo
	EMAGE:11647 same embryo
	EurExpress:euxassay_008408 same experiment
	MGI:4824643 same experiment
	Ensembl same gene
	Allen Brain Atlas same gene
	BioGPS same gene
	International Mouse Knockout Project Status same gene
	GEISHA Chicken ISH Database same gene
	EMBL-EBI Gene Expression Atlas same gene
	BrainStars same gene
	ViBrism same gene
Data Source